Publication details
Studium exprese genů podílejících se na biogenezi mikroRNA u pacientů s kolorektálním karcinomem
| Title in English | Study of expression of genes involved in microRNA biogenesis in colorectal cancer patients |
|---|---|
| Authors | |
| Year of publication | 2013 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | MicroRNAs are short non-coding single-stranded RNAs 18-25 nt long that post-transcriptionaly regulate gene expression. They have to be produced in right time on right place in optimal amount. Biogenesis of microRNAs begins with transcription, which is followed by numerous steps, which results in existence of mature microRNA molecule. Each step of this process is regulated and deregulation of the whole cascade can lead to diverse diseases including cancer. The aim of this study was to analyze the expresseion of genes involved in microRNAs biogenesis in colorectal cancer patients. |