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Způsob přípravy 1-(pyridin-4-yl)piperazinu a jeho 1,1-dialkyl-1-ium derivátů
Title in English | Process for preparing 1-(pyridin-4-yl)piperazine and 1,1-dialkyl-1-ium derivatives thereof |
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Authors | |
Year of publication | 2013 |
Type | Patent |
MU Faculty or unit | |
Publisher | |
State | Czech Republic |
Patent's number | 303950 |
web | Patentová databáze ÚPV |
Description | The new economically and environmentally advantageous process for preparing of 1-(pyridin-4-yl)piperazine and its 1,1-dialkyl-1-ium derivatives is referred. The invention is based on reaction of 4-chloropyridine or 4-cyanopyridine which is protonized or quaternized by benzyl in water or lower aliphatic alcohol C1-C3 under catalysis by d-metal or cerium in positive charged complex or in the form of compound. |
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