A Broad Phylogenetic Survey Unveils the Diversity and Evolution of Telomeres in Eukaryotes

• Authors: FULNEČKOVÁ Jana; ŠEVČÍKOVÁ Tereza; FAJKUS Jiří; LUKEŠOVÁ Alena; LUKEŠ Martin; VLČEK Čestmír; LANG B. Franz; KIM Eunsoo; ELIAS Marek; SÝKOROVÁ Eva
• Year of publication: 2013
• Type: Article in Periodical
• Magazine / Source: GENOME BIOLOGY AND EVOLUTION
• MU Faculty or unit: Central European Institute of Technology
• Doi: http://dx.doi.org/10.1093/gbe/evt019
• Field: Genetics and molecular biology
• Keywords: algae; telomerase activity; Excavata; comparative genomics; Goniomonas
• Description: Telomeres, ubiquitous and essential structures of eukaryotic chromosomes, are known to come in a variety of forms, but knowledge about their actual diversity and evolution across the whole phylogenetic breadth of the eukaryotic life remains fragmentary.These analyses confirm the human-type repeat as the most common and possibly ancestral in eukaryotes, but alternative motifs replaced it along the phylogeny of diverse eukaryotic lineages, some of them several times independently.

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• CEITEC - Central European Institute of Technology