Publication details

The 2011-12 pilot European Sentinel Registry of Transcatheter Aortic Valve Implantation: in-hospital results in 4,571 patients

Authors	MARIO Carlo Di ELTCHANINOFF Helene MOAT Neil GOICOLEA Javier USSIA Gian Paolo KALA Petr WENAWESER Peter ZEMBALA Marian NICKENIG Georg BARRERO Eduardo Alegria SNOW Thomas IUNG Bernard ZAMORANO Pepe SCHULER Gerhard CORTI Roberto ALFIERI Ottavio PRENDERGAST Bernard LUDMAN Peter WINDECKER Stephan SABATE Manel GILARD Martine WITOWSKI Adam DANENBERG Haim SCHROEDER Erwin ROMEO Francesco MACAYA Carlos DERUMEAUX Genevieve MAGGIONI Aldo TAVAZZI Luigi
Year of publication	2013
Type	Article in Periodical
Magazine / Source	EUROINTERVENTION
MU Faculty or unit	Faculty of Medicine
Citation
Doi	http://dx.doi.org/10.4244/EIJV8I12A209
Field	Cardiovascular diseases incl. cardiosurgery
Keywords	aortic valve disease; TAVI; valvular heart disease
Description	Aims: The aim of this prospective multinational registry is to assess and identify predictors of in-hospital outcome and complications of contemporary TAVI practice. Methods and results: The Transcatheter Valve Treatment Sentinel Pilot Registry is a prospective independent consecutive collection of individual patient data entered into a web-based case record form (CRF) or transferred from compatible national registries. A total of 4,571 patients underwent TAVI between January 2011 and May 2012 in 137 centres of 10 European countries. Average age was 81.4+/-7.1 years with equal representation of the two sexes. Logistic EuroSCORE (20.2+/-13.3), access site (femoral approach: 74.2%), type of anaesthesia and duration of hospital stay (9.3+/-8.1 days) showed wide variations among the participating countries. In-hospital mortality (7.4%), stroke (1.8%), myocardial infarction (0.9%), major vascular complications (3.1%) were similar in the SAPIEN XT and CoreValve (p=0.15). Mortality was lower in transfemoral (5.9%) than in transapical (12.8%) and other access routes (9.7%; p<0.01). Advanced age, high logistic EuroSCORE, pre-procedural >= grade 2 mitral regurgitation and deployment failure predicted higher mortality at multivariate analysis. Conclusions: Increased operator experience and the refinement of valve types and delivery catheters may explain the lower rate of mortality, stroke and vascular complications than in historical studies and registries.