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COGNITIVE EFFECTS OF rTMS APPLIED OVER THE RIGHT INFERIOR FRONTAL AND SUPERIOR TEMPORAL GYRI: A PILOT STUDY IN PATIENTS WITH COGNITIVE IMPAIRMENT DUE TO ALZHEIMER’S DISEASE
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Year of publication | 2013 |
Type | Appeared in Conference without Proceedings |
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Description | Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive tool for modulating cortical activity. rTMS provides an effective new method for investigating cognitive functions in human subjects and may provide treatment effects in patients with degenerative brain diseases. So far, most of the studies have focused on high frequency rTMS of the left dorsolateral prefrontal cortex (DLPFC) in these patient populations. However, using the frameless stereotaxy for the coil navigation, rTMS of other cortical areas might bring further relevant effects in cognitive rehabilitation. The right frontal gyrus has been typically implicated in response inhibition on a go/no-go task. Previous studies have revealed that inferior frontal junction (which includes also parts of Brodmann area 44) has a role in three main component processes of cognitive control (task switching, inhibitory control and working memory). The right superior temporal gyrus plays a role in attentional shift rate, independent of the stimulated modality. |