Publication details
Způsob přímé mono-N-substituce piperazinu
| Title in English | Method of piperazine direct mono-N-substitution |
|---|---|
| Authors | |
| Year of publication | 2014 |
| Type | Patent |
| MU Faculty or unit | |
| Publisher | |
| State | Czech Republic |
| Patent's number | 304520 |
| web | http://isdv.upv.cz/portal/pls/portal/portlets.pts.det?xprim=1847729&lan=cs |
| Description | The solution provides a method for the direct, mono-N-substitution in the synthetically significant yields in a simple embodiment, in which is prepared piperazin-1-ium cation and subsequently catalyzed compound d-metal, aluminum or cerium reacting piperazine-1-ium cation electrophile i. e. nitrourea agent, preferably in a molar ratio of piperazine-1-ium cation to electrophilic reagent in the range of 1:1 to 1:1.4. |
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