Publication details

Způsob přímé mono-N-substituce piperazinu

Title in English Method of piperazine direct mono-N-substitution
Authors

PAZDERA Pavel ZBEROVSKÁ Barbora NĚMEČKOVÁ Dana

Year of publication 2014
Type Patent
MU Faculty or unit

Faculty of Science

Publisher
State Czech Republic
Patent's number 304520
Web http://isdv.upv.cz/portal/pls/portal/portlets.pts.det?xprim=1847729&lan=cs
Description The solution provides a method for the direct, mono-N-substitution in the synthetically significant yields in a simple embodiment, in which is prepared piperazin-1-ium cation and subsequently catalyzed compound d-metal, aluminum or cerium reacting piperazine-1-ium cation electrophile i. e. nitrourea agent, preferably in a molar ratio of piperazine-1-ium cation to electrophilic reagent in the range of 1:1 to 1:1.4.
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