Publication details
Dítě s imunodeficientním stavem, možnosti řešení. 1.část, Diagnostické přístupy
| Authors | |
|---|---|
| Year of publication | 2014 |
| Type | Peer-reviewed scientific article |
| Magazine / Source | Pediatrie pro praxi |
| MU Faculty or unit | |
| Citation | |
| Field | Immunology |
| Keywords | imunodeficiency; IVIG; SCIG; TREC; KREC; transplantation; screening |
| Description | Early diagnosis of immunodeficiency makes possible early definitive therapy and avoids the complications of pretreatment infections. B-cell defects constitute the majority of primary immunodeficiencies. All are characterized by the reduction in or absence of immunoglobulins and/or specific antimicrobial antibodies. Consequently, substitution of immunoglobulin G (IgG) is the pillar of treatment. T-cell immunodeficiency defects become apparent as combined T- and B-cell deficiencies. |