Publication details

Diferenciální diagnostika eozinofilie

Title in English Differential diagnostics o hypereosinophilia
Authors

DOUBEK Michael BRYCHTOVÁ Yvona KISSOVÁ Jarmila TOMIŠKA Miroslav ADAM Zdeněk

Year of publication 2014
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords differential diagnostics; hypereosinophilia
Description Hypereosinophilia is characterized by chronic increase of peripheral blood eosinophiles with common damage to various organs due to eosinophilic infiltration and release of mediators. Hypereosinophylia should be both reactive and clonal, and accompanies group of heterogeneous disorders (infectious, pulmonary, immunologic, malignant). Based on recent advances in molecular and genetic diagnostic techniques and increasing experience with differences in clinical features and prognosis, some subtypes of clonal hypereosinophilic syndromes have been defined, such as myeloproliferative variants, including chronic eosinophilic leukemia, and lymphocytic variants, but other subtypes remain undefined. Differential diagnostics oh hypereosinophilie therefore remains one of very important medical issues.

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