Publication details
Stoffwechsel, Hormon- und Immunsystem
| Title in English | Metabolic, endocrine and immune system |
|---|---|
| Authors | |
| Year of publication | 2014 |
| Type | Chapter of a book |
| MU Faculty or unit | |
| Citation | |
| Attached files | |
| Description | The fact that the diabetes mellitus (DM) up to 20% of individuals seventh decade of life concerns and an additional 20% interest in a disturbed glucose tolerance (GT) suffer forms the backbone that it is clinically important metabolic disease in old age. In the seniors population occurs predominantly type 2 diabetes (for those over the age of 70 to 95%). For the development of type 2 diabetes especially following phenomena are responsible: 1. insulin resistance, 2. impairment of insulin secretion and 3. increased hepatic glucose production. At the age of DM type 2 is caused by the interaction of genetic predisposition and the influences of the external environment (eating habits, modern lifestyle, Ssress, low physical activity). DM is a significant risk factor for the formation and evolution later both micro- and macrovascular diabetic complications. The therapeutic interventions should ideally include all components of the syndrome of insulin resistance (hypertension,lipids etc.) include. Therapeutic options for type 2 DM include: diet, physical activity, oral antidiabetic agents, insulin and education. |