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Šance na vyléčení dětí s akutní lymfoblastickou leukémií stoupla v České republice v 21. století na 90 % – výsledky studie ALL IC-BFM 2002
Title in English | The prospects for children with acute lymphoblastic leukemia of being cured has increased in the Czech Republic in the 21st century to 90% - outcome of the ALL-IC BFM 2002 trial |
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Authors | |
Year of publication | 2015 |
Type | Article in Periodical |
Magazine / Source | Časopis lékařů českých |
MU Faculty or unit | |
Citation | |
web | https://www.prolekare.cz/casopisy/casopis-lekaru-ceskych/2015-2/sance-na-vyleceni-deti-s-akutni-lymfoblastickou-leukemii-stoupla-v-ceske-republicev-21-stoleti-na-90-vysledky-studie-all-ic-bfm-2002-51937 |
Field | Oncology and hematology |
Keywords | acute lymphoblastic leukemia; children; chemotherapy; protocol ALL-IC BFM 2002 |
Description | Background. Acute lymphoblastic leukemia (ALL) is the most frequent childhood malignancy. Treatment has been unified in the middle of 1980 in the Czech Republic. In 2002-2007 children and adolescents with acute lymphoblastic leukemia were treated in an international randomized trial ALL-IC BFM 2002 in the Czech Republic. 291 patients aged 1-18 years were enrolled; infants below 1 year entered a separate trial. Conclusions. In comparison with the previous trial ALL BFM 95, significant improvement was achieved. |