Publication details

Accuracy Analysis of Narrow Band Imaging (NBI) Bronchoscopy Compared To White Light Bronchoscopy in the Diagnostics of Lung Tumours

Authors

ONDREJKA Gustav MÁJEK Ondřej SKŘIČKOVÁ Jana TYL Richard

Year of publication 2015
Type Article in Periodical
Magazine / Source International Journal of Health Sciences and Research
MU Faculty or unit

Faculty of Medicine

Citation
Field Pneumology
Keywords Lung cancer; Bronchoscopy; Narrow band imaging
Description Background: Bronchoscopy plays an important role in the diagnostics of lung tumours. One of the technologies looking for their way in the diagnostics of pulmonary diseases is narrow band imaging. The aim of this study was to compare accuracy of examinations in the NBI and the white light (WL) modes in relation to biopsy results for the diagnoses of malignant tumour or severe dysplasia. Methods and results: A group of 500 patients have undergone a bronchoscopic examination in the NBI mode and afterwards in the white light. Biopsies were taken from all areas with pathological findings in both the modes for histological examination. Pathological bronchoscopic images were detected in a total of 382 patients. Positive findings in both the NBI mode and the WL mode were detected in 331 patients (66.2%). Discordant NBI-/WL+ findings were detected in 29 cases (5.8%) and discordant NBI+/WL- findings were detected in 22 cases (4.4%). The relative sensitivity of NBI compared to WL is 1.06 (p < 0.01; NBI sensitivity is significantly higher). The relative rate of false positive results in NBI compared to WL is 0.91 (p = 0.01; the rate of false positive results is significantly lower in NBI). Conclusions: The performed statistical evaluation shows a statistically significant increase in examination accuracy in NBI compared to WL. An NBI examination is able to differentiate between the necrotic avascular region of the tumour and the viable tissue very well even if an examination in the WL mode is not so explicit in this respect.

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