Publication details
Electrospinning of poly(vinyl) alcohol and hyaluronic acid
| Authors | |
|---|---|
| Year of publication | 2016 |
| Type | Article in Proceedings |
| Conference | XVI. Workshop of Physical Chemists and Electrochemists |
| MU Faculty or unit | |
| Citation | |
| Field | Physical chemistry and theoretical chemistry |
| Keywords | poly(vinyl)alcohol; hyaluronic acid; electrospinning |
| Description | Poly(vinyl) alcohol is a hydrophilic semi-crystalline polymer soluble in water that exhibits great chemical and thermal stability. This polymer is biodegradable, biocompatible and non-toxic. Due to these properties as well as the ease of its processing, it is widely used in many fields – from papermaking to the production of cosmetics, where it is used as a binding agent, emulsifier and a thickening agent. PVA is available in a variety of degrees of hydrolysis (DH) and molecular weights because it is derived from the hydrolysis (or alcoholysis) of poly(vinylacetate). Its properties are therefore dependent on the degree of hydrolysis. Hyaluronic acid (HA) is a naturally occurring polysaccharide commonly found in the connective tissues of higher animals. HA is a linear polymer belonging to the glycosaminoglycan family. HA solutions have a relatively high conductivity, which increases in direct proportion to their concentration. HA solutions also have a high viscosity and surface tension, even at relatively low concentrations. Like PVA, HA is currently widely used in cosmetics and also in the pharmaceutical industry. The aim of this work is to use the electrostatic spinning method to produce nanofibrous materials containing exclusively PVA and HA. The influence of polymer tye and solution characteristics on the preparation of nanofibrous materials will be discussed. |