Publication details

Asymptomatic Elevation of Amylase and Lipase After Olanzapine Treatment

Authors

USTOHAL Libor MAYEROVÁ Michaela VALKOVÁ Barbora SEDLÁKOVÁ Hana KAŠPÁREK Tomáš

Year of publication 2016
Type Article in Periodical
Magazine / Source JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
MU Faculty or unit

Central European Institute of Technology

Citation
web http://journals.lww.com/psychopharmacology/Citation/2016/04000/Asymptomatic_Elevation_of_Amylase_and_Lipase_After.18.aspx
Doi http://dx.doi.org/10.1097/JCP.0000000000000460
Field Pharmacology and pharmaceutical chemistry
Keywords ACUTE-PANCREATITIS
Description Olanzapine, an atypical antipsychotic,has been considered one of the most efficient antipsychotic drugs, and it is the most frequently prescribed. It is categorized as a multiacting receptor targeted antipsychotic. The most significant adverse effects of olanzapine are metabolic: acute pancreatitis is one of the most serious adverse effects; fortunately, it does not occur very often. Koller et al1 found 51 cases,and at least 13 cases have been described more precisely. We present a case study of a young female patient with a very fast and high increase of amylase and lipase, who remained asymptomatic, immediately after olanzapine treatment.
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