Publication details
Využití radioterapie v léčbě adenokarcinomu pankreatu
| Title in English | Radiotherapy in treatment of pancreatic adenocarcinoma |
|---|---|
| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Traumatology and orthopaedic surgery |
| Keywords | pancreatic adenocarcinoma; radiotherapy; chemotherapy |
| Description | Pancreatic adenocarcinoma is one of the most feared oncological diagnoses and its incidence is on the rise. The main difficulty is a lack of effective treatment options. Even when deploying all standard cancer treatments, long term survival is not a common phenomenon. Surgery is a mainstay of treatment, there is hardly any doubt about it. It is still the only curable treatment modality. Role of chemotherapy is also largely clear. Even in the early stage of disease, there is a certain risk of tumor dissemination and chemotherapy is the only way how to deal with this issue. The role of radiotherapy is less clear. Large amount of scientific data was published, disscusing the use of radiotherapy in pancreatic cancer, but results are still indeterminate. Further uncertainty about appropriateness of treatment stems from anatomical localization of pancreas, which is surrounded by radiosensitive tissues. An obvious example of this issue are different guidelines between Europe and America. The aim of this article is to summarize the main studies and to discuss in which stages of pancreatic cancer is radiotherapy an appropriate treatment option. |