Publication details
The effect of uric acid on homocysteine-induced endothelial dysfunction in bovine aortic endothelial cells.
| Authors | |
|---|---|
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Neuroendocrinology Letters |
| Citation | |
| web | https://www.ncbi.nlm.nih.gov/pubmed/20027155 |
| Keywords | uric acid, homocysteine, endothelial dysfunction |
| Description | Elevated plasma uric acid indicates an increased risk of cardiovascular diseases associated with endothelial dysfunction. However, the role of uric acid in the pathogenesis of endothelial dysfunction is still a matter of debate. It is not clear whether uric acid is a real causative risk factor, an inert marker, or even a protective molecule with respect to its antioxidant properties. We have studied the effect of uric acid on intact endothelial cells as well as cells with homocysteine-induced endothelial dysfunction. |