Publication details
Ultrasound in preoperative assessment of pelvic and abdominal spread in patients with ovarian cancer: a prospective study
| Authors | |
|---|---|
| Year of publication | 2017 |
| Type | Article in Periodical |
| Magazine / Source | Ultrasound in Obstetrics and Gynecology |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.1002/uog.15942 |
| Field | Gynaecology and obstetrics |
| Keywords | diagnostic accuracy; imaging; ovarian cancer; staging |
| Description | To analyze the accuracy of ultrasound in assessing pelvic and intra-abdominal spread in patients with ovarian cancer. Methods This prospective study enrolled all consecutive patients referred to a single gynecological oncology center for suspected ovarian cancer. We analyzed only data from patients with histologically confirmed primary ovarian cancer who were evaluated following predefined preoperative ultrasound, intraoperative and pathology protocols. We evaluated the agreement of depth of infiltration of the rectosigmoid wall, tumor spread in different peritoneal compartments and presence of metastatic retroperitoneal and inguinal lymph nodes, as determined at ultrasound, with intraoperative and histopathological findings. Results In total, 578 patients were enrolled between March 2008 and January 2013, of whom 394 met the study inclusion criteria and were analyzed; 74% of these suffered from advanced-stage cancer. Our results showed excellent agreement between ultrasound and histology in assessment of rectosigmoid wall infiltration (kappa value, 0.812; area under the receiver–operating characteristics curve, 0.898). |