Publication details

Léčba pacientů s metastatickým renálním karcinomem ve vyšším věku

Title in English Therapy possibilities for elderly patients with metastatic renal cell carcinom
Authors

POPRACH Alexandr LAKOMÝ Radek BÜCHLER Tomáš

Year of publication 2016
Type Article in Periodical
Magazine / Source Farmakoterapie
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords metastatic renal cell carcinom
Description There are currently seven metastatic renal cell carcinoma treatment options. In the first line therapy we standardly use sunitinib, pazopanib, bevacizumab with interferon alpha and sorafenib. We can treat with everolimus, axitinib or sorafenib after the first line therapy failure. Aging of the population is a phenomenon emerging in the developing countries, so we meet the elderly patients more often. These elderly patients may have many comorbidities and they often use non oncological treatments. On the other hand the calendar age does not correspond to the biological age so it should not be an obstacle to treatment with targeted therapy. The main goal of this article is a short review concerning targeted therapy for elderly patients with metastatic renal cell carcinoma.

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