Publication details
Farmakoterapie dráždivého tračníku
| Title in English | Pharmacotherapy of irritable bowel syndrome |
|---|---|
| Authors | |
| Year of publication | 2017 |
| Type | Article in Periodical |
| Magazine / Source | Praktické lékárenství |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | irritable bowel; pharmacotherapy; spasmolytics; laxatives; antidiarhoics; antidepressants |
| Description | Irritable bowel syndrome is one of the most frequent functional diseases of gastrointestinal tract. Among typical symptoms there are GIT dyscomfort, abdominal pain, bloating, and change in stool consistency and/or stool frequency. Pharmacotherapy is supplementary to dietary and regime approaches and is truly symptomatic, but it often brings patients significant relief from symptoms. This article is pharmacological review of groups of drugs used in the treatment of irritable bowel syndrome. It introduces mechanisms of action, particularities of pharmacokinetics of spasmolytics, laxatives, antidiarhoics, prokinetics, antibiotics and psychotropic drugs in the treatment of irritable bowel syndrome and their position in the current range of medicines, based on EBM and current guidelines. |