Chromosome 6q deletion correlates with poor prognosis and low relative expression of FOXO3 in chronic lymphocytic leukemia patients

• Authors: JAROŠOVÁ Marie; HRUBA M.; OLTOVÁ Alexandra; PLEVOVÁ Karla; KRUZOVA L.; KRIEGOVA E.; FILLEROVA R.; KORIŤÁKOVÁ Eva; DOUBEK Michael; LYSAK D.; PROCHAZKA V.; MRÁZ Marek; INDRAK K.; PAPAJIK T.
• Year of publication: 2017
• Type: Article in Periodical
• Magazine / Source: American Journal of Hematology
• MU Faculty or unit: Faculty of Medicine
• Doi: http://dx.doi.org/10.1002/ajh.24852
• Field: Oncology and hematology
• Keywords: Chromosome 6q
• Description: Detection of genetic changes has improved the current risk stratification in chronic lymphocytic leukemia (CLL).1,2 Among the known recurrent chromosomal abnormalities,1 6q deletion is less frequent and controversy surrounding its prognostic significance still remains.

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