Imunohistochemická analýza retrakční kapsy pars tensa ušního bubínku u dětí

• Title in English: Immunohistochemical Analysis of Pars Tensa Retraction Pocket in Children
• Authors: URÍK Milan; HURNÍK P.; ŽIAK D.; MACHAČ Josef; ŠLAPÁK Ivo; MOTYKA O.; DVOŘÁČKOVÁ J.; JABANDŽIEV Petr
• Year of publication: 2017
• Type: Article in Periodical
• Magazine / Source: Otorinolaryngologie a foniatrie
• MU Faculty or unit: Faculty of Medicine
• Field: ORL, ophthalmology, stomatology
• Keywords: retraction pocket; immunohistochemical analysis; cholesteatoma; childhood
• Description: Introduction: Immunohistochemical analysis of pars tensa retraction pocket in children. Identification of signs typical for cholesteatoma and to support the retraction theory of cholesteatoma. Methods: Standard process of immunohistochemistry of retraction pockets. For immunohistochemistry we used CD45 LCA (Leukocyte common antigen), CD31 (platelet and endothelial cell adhesion molecule), D2-40 (podoplanin - lymphatic vessels) MMP9 (matrix meta-lloproteinase 9 - degradation of extracellular matrix) Ki67 (nuclear proliferation).

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