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Publication details
Antitrombotika dnes
Title in English | Antithrombotics today |
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Authors | |
Year of publication | 2018 |
Type | Article in Periodical |
Magazine / Source | Vnitřní lékařství |
MU Faculty or unit | |
Citation | |
Web | https://www.prolekare.cz/casopisy/vnitrni-lekarstvi/2018-5-1/antitrombotika-dnes-105477 |
Keywords | anticoagulants; antithrombotics; laboratory monitoring; unfractionated heparin (UFH); low molecular weight hepariny (LMWH); novel oral anticoagulants/non vitamin K oral anticoagulants (NOAC); direct oral anticoagulants (DOAC); warfarin |
Description | Over the last 10 years some new drugs affecting blood clotting - antithrombotics - were invented. For more than half a century only warfarin and heparin were available. A better understanding of the pathways involved in activation of blood clotting, the links between these systems, and the impact of thrombosis on inflammation, have led to identification of new targets and development of new drugs, especially new antiplatelet drugs and anticoagulants. With the advent of new drugs into clinical practice, treatment options of thrombotic complications are expanding. However, it is always necessary to get familiar with the drug and its properties and to know its limitations. This is the only way to offer patients the best practices. |