Publication details
Souvisí stav zásobení organizmu vitaminem D s výsledky testování kognitivních funkcí a aktivit denního života u seniorů?
| Title in English | Do the test results of cognitive function and activities of daily life of seniors correlate with the state of Vitamin D supply to the organism? |
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| Authors | |
| Year of publication | 2018 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Keywords | Vitamin D; Cognitive function; MMSE; ADL |
| Description | Aim: The aim of our study was to establish the relationship between the supply of Vitamin D to the organism and basic parameters of self-sufficiency, which are cognitive functions stipulated in the Mini Mental State Examination (MMSE) test and Barthels test for Activities of Daily Living (ADL) among seniors. Materials and Methods: In our study we evaluated, 244 patients (65 men and 179 women) of average age 80,1 ± 7,4 (min. 65, max. 99) hospitalized at Department of Internal Medicine, Geriatrics, and General Practice of Faculty of Medicine, Masaryk University and Faculty Hospital Brno, from March 2012 to September 2012. The state of Vitamin D supply to the organism was evaluated with the help of serum Vitamin D total (1.25(OH)2D+25(OH)D), the values of MMSE and ADL were taken from the third day of hospitalization till overcoming the acute stage. The characteristics of the patients were drawn with multimorbidity index CIRS - CI (cumulative Illness Rating Scale - Comorbidity Index). Furthermore, we observed the correlation of Serum Vitamin D levels to the season of the year. Results: In our patients average concentration of vitamin D levels, MMSE, and ADL was 37,9 ± 26,1 (8-142 nmol/l), 23,36 ± 6,91 (0-30 points), 80,66 ± 25,13 (0-100 points), and CIRS CI 4,7+1,9 points, respectively. The correlation of vitamin D serum level with MMSE was r = 0,289, (p ? 0.01), with ADL r = 0,292 (p ? 0.01), and CIRS CI r = - 0,22 (p < 0,05). Using multivariation analysis proved the significance of correlations obtained, even after the exclusion of multimorbidity. There was no statistically significant correlation between seasons of the year and serum vitamin D total level. However, nonsignificant decreasing trend of serum vitamin D total level with rising age of patients was found (r = - 0,149, NS). |
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