Publication details
Fast and accurate compensation of signal offset for T2 mapping
| Authors | |
|---|---|
| Year of publication | 2019 |
| Type | Article in Periodical |
| Magazine / Source | Magnetic Resonance Materials in Physics, Biology and Medicine |
| MU Faculty or unit | |
| Citation | |
| Web | https://doi.org/10.1007/s10334-019-00737-3 |
| Doi | http://dx.doi.org/10.1007/s10334-019-00737-3 |
| Keywords | Algorithms; Least-squares analysis; Software |
| Description | T2 maps are more vendor independent than other MRI protocols. Multi-echo spin-echo signal decays to a non-zero offset due to imperfect refocusing pulses and Rician noise, causing T2 overestimation by the vendor's 2-parameter algorithm. The accuracy of the T2 estimate is improved, if the non-zero offset is estimated as a third parameter. Three-parameter Levenberg--Marquardt (LM) T2 estimation takes several minutes to calculate, and it is sensitive to initial values. We aimed for a 3-parameter fitting algorithm that was comparably accurate, yet substantially faster. |