Publication details
Electrophysiological correlates of physiological déjà vu phenomenon
| Title in English | Electrophysiological correlates of physiological déja vu phenomenon |
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| Authors | |
| Year of publication | 2019 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Déja vu is the subjective experience of familiarity combined with the knowledge that this experience is false. In healthy subjects, déja vu is thought to be triggered by the dissociation of explicit and implicit memory (episodic recall vs. familiarity). Pathological form of this phenomenon is frequent in patients with temporal lobe epilepsy, which is characterized by cortical hyperexcitability and decreased volumes of temporal lobe structures. Similarly decreased volumes of medial temporal structures were observed in healthy subjects experiencing non-pathological déja vu. Another link was suggested between cortical excitability and frequency of other anomalous behavioural experiences. However, the role of cortical excitability in the genesis of déja vu has not been directly examined. In the proposed study we explore a relationship of cortical excitability to déja vu genesis in healthy subjects. We hypothesize that healthy subjects with a higher frequency of déja vu experience express increased cortical excitability compared to subjects with no déja vu experience. Cortical excitability is measured using behavioural Pattern glare task, EEG power spectral analysis, MR spectroscopy (neurotransmitter concentration), and amplitude of transcranial evoked potentials (TEPs). Psychological questionnaires are used to assess the subjects’ personality traits. This multi-method approach will allow us to evaluate the accuracy of different methods for measuring excitability in healthy population as well. |
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