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Publication details
Syndrom maligní hypertermie
Title in English | Malignant hyperthermia syndrome |
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Authors | |
Year of publication | 2019 |
Type | Chapter of a book |
MU Faculty or unit | |
Citation | |
Attached files | |
Description | Malignant hypertension can be defined as a rare but potentially life-threatening pharmacogenetic disease. After exposure to triggers, which are all volatile anesthetics and depolarizing relaxants, a genetically predisposed individual develops a pathological hypermetabolic response associated with a rapid and uncontrolled rise in myoplasmic Ca 2+, in the most severe cases ending in multiorgan failure and death. |