Publication details

Study of Synthetic Oligonacleotides Containing Guanine by Voltammetry on a Graphite Electrode

Authors

OUTLÁ Martina ŠPAČEK Jan FOJTA Miroslav HAVRAN Luděk RENČIUK Daniel

Year of publication 2018
Type Article in Proceedings
Conference PROCEEDINGS OF THE INTERNATIONAL CONFERENCE MODERN ELECTROCHEMICAL METHODS XXXVIII
MU Faculty or unit

Faculty of Science

Citation
web https://asep.lib.cas.cz/arl-cav/cs/detail-cav_un_epca-0506554-Study-of-Synthetic-Oligonacleotides-Containing-Guanine-by-Voltammetry-on-a-Graphite-Electrode/
Keywords Oligonucleotides; Pyrolytic graphite electrode; Linear sweep voltammetry
Description Electrochemical oxidation of specifically designed DNA hexamers containing guanine has been studied in aqueous acetate buffet (pH 5) at a pyrolytic graphite electrode (PGE) by linear sweep voltammetry (LSV) Influence of the oligonucleotide composition and concentration was investigated It seems that short oligonucleotides containing guanine produce oxidation signals. which are sensitive to their structural properties Simple electrochemical techniques us may be useful tool for monitoring of structural changes of DNA.

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