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Publication details
Baseline Chest Computed Tomography as Standard of Care in High-Risk Hematology Patients
Authors | |
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Year of publication | 2020 |
Type | Article in Periodical |
Magazine / Source | Journal of Fungi |
MU Faculty or unit | |
Citation | |
web | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151030/pdf/jof-06-00036.pdf |
Doi | http://dx.doi.org/10.3390/jof6010036 |
Keywords | invasive aspergillosis; chest computed tomography; hematological patient |
Attached files | |
Description | Baseline chest computed tomography (BCT) in high-risk hematology patients allows for the early diagnosis of invasive pulmonary aspergillosis (IPA). The distribution of BCT implementation in hematology departments and impact on outcome is unknown. A web-based questionnaire was J. Fungi 2020, 6, 36 3 of 13 designed. International scientific bodies were invited. The estimated numbers of annually treated hematology patients, chest imaging timepoints and techniques, IPA rates, and follow-up imaging were assessed. In total, 142 physicians from 43 countries participated. Median estimated IPA rate was 8% and did not differ between BCT (9%; IQR 5–15%) and non-BCT centers (7%; IQR 5–10%) (p = 0.69). In high-risk hematology patients, baseline CT is becoming a standard-of-care. Chest X-ray, while inferior, is still widely used. Randomized, controlled trials are needed to investigate the impact of BCT on patient outcome. |