Publication details
Závažná hypernatremie u kojence s vývojovou vadou centrální nervové soustavy
| Title in English | Severe hypernatremia in an infant with a central nervous system developmental disorder |
|---|---|
| Authors | |
| Year of publication | 2020 |
| Type | Article in Periodical |
| Magazine / Source | Pediatrie pro praxi |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.pediatriepropraxi.cz/artkey/ped-202004-0013_zavazna_hypernatremie_u_kojence_s_vyvojovou_vadou_centralni_nervove_soustavy.php |
| Doi | http://dx.doi.org/10.36290/ped.2020.059 |
| Keywords | hypernatremia; polyuria; diabetes insipidus; holoprosencephaly |
| Description | We present acase report of an infant with septooptic dysplasia variant (holoprosencephaly spectrum) with accidentally found severe hypernatremia. The case report points to the possibility of coincidence of hypopituitarism in patients with this form of forebrain malformation. Combined primary endocrine deficits in neonates and infants may result in derangement of body internal environment. Severe hypernatremia due to central diabetes insipidus is one of the potentially fatal complications requiring avery gradual, strictly controlled correction of the internal environment parameters. This is the only way to prevent serious neurological complications due to the rapidly changing internal environment. |