Publication details

Překvapivý nález v kostní dřeni: co za ním je?

Title in English Surprising findings in the bone marrow: What lies behind it?
Authors

HORŇÁK Tomáš HOLTÁNOVÁ Natália KŘEN Leoš SKŘIČKOVÁ Jana HRAZDIROVÁ Anna MAYER Jiří ŽÁČKOVÁ Daniela

Year of publication 2020
Type Article in Periodical
Magazine / Source Transfuze a hematologie dnes
MU Faculty or unit

Faculty of Medicine

Citation
web https://www.prolekare.cz/casopisy/transfuze-hematologie-dnes/2020-2-26/prekvapivy-nalez-v-kostni-dreni-co-za-nim-je-123590
Keywords atypical mycobacteria; infection; granulomatous inflammation; pancytopenia
Description This case study describes the complex diagnostic and therapeutic process in an immunocompetent patient suffering from a disseminated nontuberculous mycobacteria infection caused by Mycobacterium avium complex. During the infection, the patient suffered from pancytopenia, liver damage and acute renal failure. Necrotizing granulomatosis was found in bone marrow and splenic tissue with no signs of infection macroscopically or using imaging methods. Diagnosis was eventually determined by microbial cultivation of splenic tissue. The patient was then prescribed targeted antituberculotic treatment, which led to clinical and laboratory improvement.

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