Publication details
Interacting effects of the MAM model of schizophrenia and antipsychotic treatment: Untargeted proteomics approach in adipose tissue
| Authors | |
|---|---|
| Year of publication | 2021 |
| Type | Article in Periodical |
| Magazine / Source | Progress in Neuro-Psychopharmacology & Biological Psychiatry |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.sciencedirect.com/science/article/pii/S0278584620304814?via%3Dihub |
| Doi | http://dx.doi.org/10.1016/j.pnpbp.2020.110165 |
| Keywords | Antipsychotics; Adipose tissue; Schizophrenia; Animal model; Proteomics; Methylazoxymethanol |
| Description | Highlights Proteomics show deregulated mTOR in adipose tissue of schizophrenia-like rat model. Antipsychotics alter adipose proteome in schizophrenia-like rats but not in controls. Different antipsychotics have a distinct impact on the adipose tissue proteome. Antipsychotics modify metabolic and energetic pathways in adipose tissue. |
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