Publication details

Retinal arteriolar and venular diameters are widened in patients with schizophrenia

Authors

HOSÁK Ladislav ZEMAN Tomáš STUDNIČKA Jan STEPANOV Alexandr USTOHAL Libor MICHALEC Marek LOCHMAN Jan JUREČKA Tomáš SADYKOV Evgenii GOSWAMI Nandu DE BOEVER Patrick BALCAR Vladimír Josef ŠERÝ Omar

Year of publication 2020
Type Article in Periodical
Magazine / Source Psychiatry and Clinical Neurosciences
MU Faculty or unit

Faculty of Science

Citation
web https://doi.org/10.1111/pcn.13123
Doi http://dx.doi.org/10.1111/pcn.13123
Keywords Retina Blood Vessel; Hypertension Retinopathy; Retina Vein
Description Cerebrovascular abnormalities have been discussed as pathological mechanisms involved in schizophrenia, particularly in the context of the genetic–inflammatory–vascular hypothesis.1 The cerebral and retinal microcirculation have similarities with respect to morphology and physiology. It can therefore be tested if retinal vessel changes occur in patients with schizophrenia. Larger diameters of retinal venules have been noted in schizophrenia,2, 3 while smaller retinal arteriolar diameters were recently shown in psychoses.3 Our study aimed to contribute new information to further test the hypothesis of the ‘eye as a window to the brain’ in the context of schizophrenia.

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