Publication details

Nejvýznamnější nežádoucí účinky neopioidních analgetik a jejich farmakologické mechanismy

Title in English The most significant side effects of non-opioid analgesics and their pharmacological mechanisms
Authors

KOTOLOVÁ Hana NOVÁKOVÁ Jana

Year of publication 2020
Type Article in Periodical
Magazine / Source Neurologie v praxi
MU Faculty or unit

Faculty of Pharmacy

Citation
web https://www.neurologiepropraxi.cz/artkey/neu-202006-0012_nejvyznamnejsi_nezadouci_ucinky_neopioidnich_analgetik_a_jejich_farmakologicke_mechanismy.php
Doi http://dx.doi.org/10.36290/neu.2020.108
Keywords non-steroidal anti-inflammatory drugs; cyclooxygenase; side effects
Description Analgesics belong to the most commonly prescribed drugs. Non-opioid analgesics are drugs of various chemical origin that have analgesic, antipyretic and some of them also have anti-inflammatory and antiaggregation effect. They can be divided into analgesics - antipyretics and non-steroidal anti-inflammatory drugs. Inhibition of cyclooxygenase and thus influencing the formation of eicosanoids is a common mechanism of action, especially in nonsteroidal antiphlogistics. Both desirable therapeutic effects and side effects are associated with the influencing of eicosanoid production.

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