Publication details

Tropheryma whipplei jako původce infekční endokarditidy

Title in English Tropheryma whipplei as a causative agent of infectious endocarditis
Authors

HUDEC Martin BRÁZDIL Vojtěch RADVAN Martin KOC Lumír KAŇOVSKÝ Jan GÁL Roman SEKERKA Jan KALA Petr

Year of publication 2021
Type Article in Periodical
Magazine / Source Cor et Vasa Case Reports
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.cksonline.cz/coretvasa-case-reports/clanky.php?p=detail&id=142&pid=1445
Keywords BCNIE; Culture-negative infective endocarditis; Tropheryma whipplei; TWIE; Whipple’s disease
Description Tropheryma whipplei is the cause of the very rare Whipple’s disease. There are both classical and atypical forms described and both of them can affect heart valves. The disease belongs to the group of blood-culture negative infective endocarditis (BCNIE), because it’s difficult to cultivate the pathogen. However, percentage of BCNIE in total amount of infective endocarditis is not negligible. There is a relatively small number of documented cases in literature. It might be easily omitted in clinical practice. Moreover, diagnosis is very difficult as it is crucial to think about the possibility of the disease. In most cases, surgical resection of valve is necessary and consequential long-term antibiotic therapy is administered. The described case report is one of the few in our region and aims to raise awareness of this IE agent.

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