First Autochthonous West Nile Lineage 2 and Usutu Virus Infections in Humans, July to October 2018, Czech Republic

• Authors: ZELENÁ Hana; KLEINEROVÁ Jana; ŠIKUTOVÁ Silvie; STRAKOVÁ Petra; KOCOURKOVÁ Hana; STEBEL Roman; HUSA Petr; HUSA Petr; TESAŘOVÁ Eva; LEJDAROVÁ Hana; ŠEBESTA Oldřich; JURÁŠ Peter; CIUPEK Renata; MRÁZEK Jakub; RUDOLF Ivo
• Year of publication: 2021
• Type: Article in Periodical
• Magazine / Source: Pathogens
• MU Faculty or unit: Faculty of Medicine
• Web: https://www.mdpi.com/2076-0817/10/6/651/htm
• Doi: http://dx.doi.org/10.3390/pathogens10060651
• Keywords: West Nile virus; Usutu virus; mosquito-borne infections; human
• Description: We present epidemiological, clinical and laboratory findings of five Czech patients diagnosed with autochthonous mosquito-borne disease-four patients with confirmed West Nile virus (WNV) and one patient with Usutu virus (USUV) infections, from July to October 2018, including one fatal case due to WNV. This is the first documented human outbreak caused by WNV lineage 2 in the Czech Republic and the first record of a neuroinvasive human disease caused by USUV, which illustrates the simultaneous circulation of WNV and USUV in the country.