Publication details
Účinky koňského kolagenu a kyseliny hyaluronové v terapii bércového vředu - případová studie
| Title in English | Effects of equine collagen and hyaluronic acid in the treatment of crural ulcers - a case study |
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| Authors | |
| Year of publication | 2021 |
| Type | Article in Periodical |
| Magazine / Source | Léčba ran |
| MU Faculty or unit | |
| Citation | |
| Web | http://www.vzdelavani-in.cz/casopis/ |
| Keywords | crural ulcer; venous insufficiency; hyaluronic acid; horse collagen |
| Description | Introduction: Etiology of about 80 % of all crural ulcers is venous. The treatment of these defects is often difficult and the right choice of wet healing aids helps to speed up the therapy significantly. One new method for local treatment of crural ulcers is the use of wet healing dressing combining equine collagen type I and hyaluronic acid, which support the correct anchoring of fibroblasts and the proper deposition of endogenous collagen. Case report: A 40year old man comes to the chronic wound clinic for 1 year of non-healing spontaneous leg ulcer. He was temporarily treated at the dermatological clinic, the defect healed for a while, then reopened. Furthermore, the patient underwent local treatment of the wound by the wound healing nurse, the dressings with iodine powder and disinfectant were used. He had no vascular examination. In our clinic an initial vascular examination was performed, according to an ultrasound finding, the insufficiency of the saphenous-femoral junction was revealed with reflux into the dilated great saphenous vein, which continued directly to the defect area. There had been indicated the surgical procedure (removal of reflux and great saphenous vein), which was contraindicated for adverse cardiac findings. Therefore, so far only phlebectomy in the area of the defect under local anesthesia was performed. Wet healing started: after debridement, we used Hyalo4 Silver Spray (1 week) and then Hyalo4 Regen (9 weeks). After 10 weeks of treatment in our outpatient clinic (debridement, phlebectomy, Hyalo4 wet healing agents) the defect has been completely healed. The indication for vascular surgery reamains. Conclusion: Therapy of crural ulcers requires a comprehensive approach, both in local therapy and in the diagnosis and treatment of the major disease. The right choice of moist healing agents can significantly speed up the therapy process. Among the modern means of wet healing with excellent clinical results is the use of equine collagen type I in combination with hyaluronic acid. Supported by: MUNI/A/1246/2020 |
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