Publication details
Aseptic meningitis during acute hepatitis E - single center experience
| Authors | |
|---|---|
| Year of publication | 2021 |
| Type | Article in Periodical |
| Magazine / Source | Ceska a slovenska neurologie a neurochirurgie |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.csnn.eu/casopisy/ceska-slovenska-neurologie/2021-6-7/asepticka-meningitida-pri-akutni-hepatitide-e-zkusenosti-z-jednoho-centra-129381 |
| Doi | http://dx.doi.org/10.48095/cccsnn2021572 |
| Keywords | Aseptic meningitis; acute hepatitis E |
| Description | We would like to describe two rare cases of CNS involvement (aseptic meningitis) in immunocompetent patients with acute hepatitis E, treated at the Department of Infectious Diseases, University Hospital Brno, Czech Republic. In the last decade, it has been recognized that hepatitis E virus (HEV) is also endemic in the CR with the incidence of about 2.6/ 100 000 inhabitants. Most cases of hepatitis E in Europe arise from infected animals such as pigs, wild boar, deer and rabbits. Zoonotic HEV genotypes (HEV genotypes 3–8) are mainly food-borne or transmitted by direct contact, but recent data suggest that infection can also be water-borne or iatrogenic through contaminated blood products. Most patients with acute hepatitis E have no symptoms or the symptoms are indistinguishable from other forms of acute viral hepatitis. There have been several extrahepatic manifestations reported with hepatitis E. We present two cases of neurological involvement in patients with acute hepatitis E, hospitalized from 2018–2020. |