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Publication details
Mass Spectrometry Imaging Techniques Enabling Visualization of Lipid Isomers in Biological Tissues
Authors | |
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Year of publication | 2022 |
Type | Article in Periodical |
Magazine / Source | Analytical Chemistry |
MU Faculty or unit | |
Citation | |
web | https://pubs.acs.org/doi/10.1021/acs.analchem.1c05108 |
Doi | http://dx.doi.org/10.1021/acs.analchem.1c05108 |
Keywords | mass spectrometry imaging; lipid isomers; double bond position; sn-position; chemical derivatization; biological tissues |
Description | The feature article focuses on a review of recent developments in mass spectrometry imaging (MSI) of lipid isomers in biological tissues. The tandem MS techniques utilizing on-line and off-line chemical derivatization procedures, ion activation techniques such as ozone-induced dissociation (OzID), ultraviolet photodissociation (UVPD), or electron-induced dissociation (EID), and other techniques such as coupling of ion mobility with MSI are discussed. The importance of resolving lipid isomers in diseases is highlighted. |
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