Publication details

Oxidation processes of N-methylguanines

Authors

TRNKOVÁ Libuše TŘÍSKOVÁ Iveta LIŠKA Alan LUDVÍK Jiří

Year of publication 2021
Type Article in Proceedings
Conference XL. Moderní elektrochemické metody
MU Faculty or unit

Faculty of Science

Citation
Web https://www.bestservis.eu/images/file/Sbornik_metody21.pdf
Keywords Guanine; N-methylated guanine; Oxidation process; Voltammetry; HOMO (SOMO) energy; DFT methods; Epigenetic modification
Description The oxidation processes of N-methylguanines were investigated in both experimental and theoretical way. Voltammetric oxidation potentials of guanine and its methyl analogues, acquired on polymer pencil graphite electrode (pPeGE), were compared with the HOMO (SOMO) energies calculated by density functional (DFT) methods. Our study contributes to understanding not only the oxidation processes of methylated guanines but also their role in epigenetics.
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