Metal Oxide Laser Ionization Mass Spectrometry Imaging of Fatty Acids and Their Double Bond Positional Isomers

• Authors: KOKTAVÁ Monika; VALÁŠEK Jan; BEZDEKOVÁ Dominika; PRYSIAZHNYI Vadym; ADAMOVÁ Barbora; BENEŠ Petr; NAVRÁTILOVÁ Jarmila; HENDRYCH Michal; VLČEK Petr; PREISLER Jan; BEDNAŘÍK Antonín
• Year of publication: 2022
• Type: Article in Periodical
• Magazine / Source: Analytical Chemistry
• MU Faculty or unit: Faculty of Science
• web: https://pubs.acs.org/doi/10.1021/acs.analchem.2c00551
• Doi: http://dx.doi.org/10.1021/acs.analchem.2c00551
• Keywords: ozone; fatty acids; metal oxide; metal oxide laser ionization; MOLI MS; mass spectrometry imaging; MSI; double bond position; lipid isomers
• Description: The article presents a novel combination of metal oxide laser ionization mass spectrometry imaging (MOLI MSI) technique with off-line lipid derivatization by ozone for the detection of fatty acids (FA) and their carbon-carbon double bond (C=C) positional isomers in biological tissues.

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