Publication details
The hypothyroid state restricts the conversion of regenerating soleus muscle grafted into fast EDL muscle
| Authors | |
|---|---|
| Year of publication | 1998 |
| Type | Article in Periodical |
| Magazine / Source | Journal of Physiology (London) [IF=4.727 (1997); SCI #cit.<1>] |
| MU Faculty or unit | |
| Citation | |
| Field | Morphological specializations and cytology |
| Keywords | regenerating soleus muscle; EDL muscle; hypothyroid state |
| Description | Soleus (SOL) muscles of 21- to 28-day-old inbred rats of the Lewis strain were grafted into the fast extensor digitorum longus (EDL) muscles in young adult euthyroid, hyperthyroid or hypothyroid inbred rats of the same strain. One to 3 months after the operation, rats were killed and muscle histochemical profiles and expression of myosin heavy chain (MyHC) isoforms were determined. It can be concluded that normal levels of thyroid hormones are required for the expression of the fast MyHC isoforms in the regenerating SOL muscle reinnervated by the fast EDL nerve. |