Publication details
Bromide kinetics and distribution in the rat. I. Biokinetics of 82Br-bromide.
| Authors | |
|---|---|
| Year of publication | 2000 |
| Type | Article in Periodical |
| Magazine / Source | Biological Trace Element Research [IF=0.786 (1999); SCI #cit.<7>] |
| MU Faculty or unit | |
| Citation | |
| Field | Physiology |
| Keywords | Bromide;biokinetics;biological half-life;bromide space;radionuclide 82-Br; rat |
| Description | Biological half-lives of bromine in 15 different organs and tissues of the rat, in addition to the whole-body half-life, were determined by measuring the radioactive concentration of 82Br-bromide in samples of tissues collected at the time intervals of 12-396 h from animals that continuously (up to 17 d) received 82Br-labeled bromide in their drinking water. In most of the studied tissues, the biological half-lives of bromine were shorter than in the whole body, in which it equalled 197.8+22.2 h. Significant correlation between the values of the steady-state concentration of bromide and of the biological half-life was found for most tissues. |