Publication details

IMPACT OF ADMINISTRATION METHOD OF THROMBOLYTICS ON THEIR THROMBOLYTIC EFFECTS

Authors

DAVUT AKSU Ahmet HLOŽKOVÁ Jana SCHEER Peter BRHELOVÁ Eliška MIČAN Jan TOUL Martin DAMBORSKÝ Jiří KAŠPÁREK Petr DOLAŽALOVÁ Jana MIKULÍK Robert

Year of publication 2022
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Pharmacy

Citation
Attached files
Description Our experimental outcome demonstrated that new potential thrombolytic ALT 04 administered in a continuous rate infusion regimen have only a minimal thrombolytic effect, in contrast to the bolus application depending on the relative change of AC area at 60 min. The new substance ALT 04 0.9 mg/kg in IVB administration route showed a better thrombolytic effect than alteplase 0,9 mg/kg in CRI non-significantly. Testing of other ALT 04 concentrations is the subject of further promising research.
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