Publication details
Paulownia tomentosa extracts fighting against staphylococcal biofilm formation
| Authors | |
|---|---|
| Year of publication | 2023 |
| Type | Appeared in Conference without Proceedings |
| MU Faculty or unit | |
| Citation | |
| Description | Staphylococcus aureus is challenging to treat especially if biofilm occurs. Prenylated phenolics provide a significant source of potent antimicrobial agents. Ethanolic extract of Paulownia tomentosa was rich in active compounds, but prenylated flavonoids were dominant in the chloroform fraction. MIC of ethanolic extract, chloroform fraction, and three flavonoids showed significant antimicrobial activity, while lower concentrations prolonged the lag phase. Selected compounds reduced the adhesion of bacteria to the abiotic surface, and also the measurement of bioluminescence showed inhibition of intercellular signaling in bacterial suspension treated with plant formulations. |
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