Publication details
Synthesis of Enantiomerically Pure Bambus[6]urils Utilizing Orthogonal Protection of Glycolurils
| Authors | |
|---|---|
| Year of publication | 2023 |
| Type | Article in Periodical |
| Magazine / Source | Journal of Organic Chemistry |
| MU Faculty or unit | |
| Citation | |
| web | https://pubs.acs.org/doi/10.1021/acs.joc.3c00667 |
| Doi | http://dx.doi.org/10.1021/acs.joc.3c00667 |
| Keywords | FLUORINATED BAMBUSURILS; DEPROTECTION; RECOGNITION; CUCURBITURIL; CATALYSTS; BINDING; WATER; ALKYL |
| Attached files | |
| Description | A general strategyfor the synthesis of 2N,4N & PRIME;-disubstitutedglycoluril enantiomers on a multigramscale using orthogonal protection is reported. The use of these glycolurilsis demonstrated in the synthesis of enantiomerically pure bambus[6]urilmacrocycles. Moreover, the deprotection of (S)-1-phenylethylsubstituents on the macrocycle was achieved, opening access to variouschiral bambus[6]urils via post-macrocyclization modificationstrategy. |
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