Publication details

Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?

Authors

TÝČOVÁ Anna PŘIKRYL Jan HEMZAL Dušan

Year of publication 2023
Type Article in Periodical
Magazine / Source TrAC Trends in Analytical Chemistry
MU Faculty or unit

Faculty of Science

Citation
web https://doi.org/10.1016/j.trac.2023.117017
Doi http://dx.doi.org/10.1016/j.trac.2023.117017
Keywords Coupling; Detection; Electromigration; Electrophoresis; Nanoparticles; Nanostructures; Raman spectroscopy; Separation; Surface-enhanced Raman spectroscopy; Substrate
Description In the past, many detection principles have been developed to trace narrow zones separated via capillary electrophoresis (CE) with various sensitivity and selectivity. While some of them have become mature technologies that are routinely used coupled online with CE, other ones will require further intensive investigation. This is the case of Raman spectroscopy and surface-enhanced Raman spectroscopy (SERS) which operate with inelastically scattered photons. The enormously rich chemical and structural infor-mation encoded in Raman spectra continuously attracts the attention of researchers striving to develop a robust and reliable coupling of CE and Raman/SERS. In this paper, we provide a systematic overview of the achievements attained in this field with a special focus on the practical aspects that present chal-lenges to CE-Raman/SERS coupling. We also discuss possible future development in this field.(c) 2023 Elsevier B.V. All rights reserved.
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