Publication details
The Effect of CNQX on Self-Administration: Present in Nicotine, Absent in Methamphetamine Model
| Authors | |
|---|---|
| Year of publication | 2024 |
| Type | Article in Periodical |
| Magazine / Source | FRONTIERS IN BEHAVIORAL NEUROSCIENCE |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1305412/full |
| Doi | http://dx.doi.org/10.3389/fnbeh.2023.1305412 |
| Keywords | AMPA/kainate receptor; CNQX; Nicotine; Methamphetamine; Self-administration; Relapse |
| Description | CNQX significantly reduced nicotine intake during the maintenance phase, but no effect was revealed on nicotine seeking after forced abstinence. CNQX did not affect methamphetamine taking or seeking. The effect of reducing nicotine taking but not seeking could be explained by different involvement of glutamatergic receptors in various stages of nicotine dependence. |
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