Exploring patterns in clinical, biological, and molecular data of leukemia patients with CLLue.

• Authors: REIGL Tomáš; NAVRKALOVÁ Veronika; PORC Jakub Paweł; PÁL Karol; STRÁNSKÁ Kamila; POSPÍŠILOVÁ Šárka; PLEVOVÁ Karla
• Year of publication: 2023
• Type: Conference abstract
• MU Faculty or unit: Central European Institute of Technology

Attached files

• CEITEC_PhD_conference_Abstract_book.pdf

• Description: High throughput sequencing data analysis of IG/TR rearranged genes in leukemia clinical research', he has been involved in the development of several software projects, e.g.: LYNX (LYmphoid NeXt-Generation Sequencing) analytical software, CLLue, ARResT/Interrogate, ARResT/Subsets aka Encyclopedia of CLL Subsets. LYNX is a tailor-made bioinformatic tool for a new custom-designed capture-based NGS panel. With this tool, a user can analyze molecular markers, such as gene mutations, copy number variations, antigen receptor rearrangements, and translocations in the most common lymphoid malignancies. CLLue is an interactive web-based tool that allows users to perform a visual exploratory data analysis, identification of important and significant features in given groups based on statistical tests, and de novo clustering on their data.

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