Publication details
Synthesis and evaluation biological activity of newly designed hydroxamates as potential HDAC inhibitors
| Title in English | Synthesis and evaluation of biological activity of newly designed hydroxamates as potential HDAC inhibitors |
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| Authors | |
| Year of publication | 2023 |
| Type | Appeared in Conference without Proceedings |
| MU Faculty or unit | |
| Citation | |
| Description | Histone deacetylase inhibitors (HDACi) represent a relatively new generation of drugs with the ability to affect the expression of specific genes, which can repair controlled proliferation or damage apoptotic processes in tumor cells. HDAC inhibitors have considerable anticancer activity forming a complex with the Zn2+ ion in the catalytic pocket of enzymes.2 |
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