Publication details
Okrelizumab v rozdílných indikacích
| Title in English | Okrelizumab in different indications |
|---|---|
| Authors | |
| Year of publication | 2023 |
| Type | Article in Periodical |
| Magazine / Source | Multiple sclerosis News |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.worldmednet.cz/okrelizumab-v-rozdilnych-indikacich/ |
| Keywords | Okrelizumab; multiple sclerosis |
| Description | Multiple sclerosis (MS) is a chronic, immune-mediated neurological disease of the central nervous system. The inflammatory process and inflammation-triggered neurodegeneration play an important role in the pathogenesis of the disease. B-lymphocytes are thought to be the key factors responsible for tissue involvement. In recent years, attention has therefore focused on the development of anti-CD20 monoclonal antibodies that selectively deplete B-cells. |