Publication details

Okrasné dřeviny jako zdroj biologicky aktivních látek

Title in English Ornamental trees as the source of compounds with potential biological activity
Authors

DVORSKÁ Margita

Year of publication 2023
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Pharmacy

Citation
Description The increase of civilization diseases, infections, problems with antibiotic resistance, etc. leads to the searching for new compounds with specific biological activity. The plant sources of these substances usually come from plants historically used in the traditional medicine of various countries. These are not always representatives of native domestic species, so there may be a problem with their availability. A suitable alternative can be plants used somewhere only for ornamental purposes, but for which the professional literature describes potential or already confirmed biological effects. E.g. antioxidant, antimicrobial, anti-inflammatory or cytotoxic activity is often mentioned. Very interesting compounds were isolated for example from plant genera Paulownia, Maclura, Catalpa and others. In Paulownia trees geranyl flavonoids are typically co nnected with the biological effects same as prenyl flavonoids and xanthones from Maclura spp. or iridoids isolated from Catalpa spp. Information about distribution of active secondary metabolites in certain species, evaluation of structure/effect relationship and next biological studies are necessary part of research of potential natural drugs. Ornamental plants so could be suitable and available source enabling targeted phytochemical studies and the isolation of potentially therapeutically usable compounds.
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